If the loved one plans to sit with the patient during the ketamine treatment, cell phones should be in silent mode, and the loved one should avoid making loud noises or excessive movement around the room that might distract the patient. It is best for loved ones to stay quiet and not to initiate conversation with the patient directly as they might be confused or surprised by the interaction. Patients can have a wide range of responses to ketamine, including excitement, confusion, become chatty, or go quiet. Patients might even want someone to hold their hand during treatment, and if the loved one is comfortable, it is ok to provide that support. The patient might also express how they are feeling during treatment or ask questions about who they are, where they are, or if they are alive. These are normal responses to the dissociative experience, so whatever happens, it is important for loved ones to stay calm and supportive during the process. If the loved one has any questions or concerns, they are best addressed to the medical staff outside the room.