What patients experience, depends on many factors, such as mode of administration (e.g., intravenous, intramuscular, intranasal, etc.), dose of ketamine, individual sensitivity to ketamine, amongst others. For most patients that receive subanesthetic doses to treat psychiatric and pain conditions the experience is pleasant and calming. It can induce a sense of disconnection to patients’ bodies, and a distortion of patients’ senses, such as vision, hearing, orientation to time, and others. For some, it can be disorienting, anxiety provoking, and unpleasant.